Interactive transcript · 188 lines
Good morning, everyone.
早上好，大家。
Welcome back to TalkCast, your essential morning news digest.
欢迎回到 TalkCast，您必备的早间新闻摘要。
I am Zoe, your lead anchor.
我是佐伊，您的首席主播。
And I am Lucas.
而我是卢卡斯。
Good morning, listeners.
早上好，听众朋友们。
It is fantastic to have you with us bright and early on this beautiful morning of September 9th, 2026.
能在2026年9月9日这个美好的清晨大清早有您相伴，真是太棒了。
Grab your cup of coffee or tea and let's get ready to learn some English and discover what is
端起您的咖啡或茶，准备好一起学习英语并探索正在发生的
happening around the world.
世界各地发生的大事吧。
Before we begin our headlines, we want to say a huge thank you to all our TalkCast members.
在开始我们的头条新闻之前，我们要向所有 TalkCast 会员表示巨大的感谢。
Your financial support allows us to research, write, and produce this podcast every single day.
您的资金支持使我们能够每天研究、撰写和制作这档播客节目。
Yes, thank you so much.
是的，非常感谢大家。
If you have not joined yet, please consider becoming a TalkCast member.
如果您还没有加入，请考虑成为 TalkCast 会员。
Our show is completely listener supported and we really need your help to keep bringing you these
我们的节目完全由听众支持，我们非常需要您的帮助来继续为您带来这些
high quality daily episodes.
高质量的每日节目。
Now, let's take a quick look at what is making headlines today.
现在，让我们快速浏览一下今天登上头条的内容。
We have some incredibly exciting and important stories to share with you.
我们有一些极其令人兴奋和重要的故事要与您分享。
We certainly do, Zoe.
我们确实有，佐伊。
First up, we will talk about a groundbreaking drug discovered by artificial intelligence that might
首先，我们将讨论一种由人工智能发现的开创性药物，它可能
actually reverse biological aging.
实际上能够逆转生物衰老。
Then, we will look at a serious new health warning regarding a very popular sugar substitute.
然后，我们将关注一项关于一种非常受欢迎的代糖替代品的严重新健康警告。
After that, we will explore a fascinating new concept called eating jet lag and how inconsistent
在此之后，我们将探索一个名为“饮食时差”的有趣新概念，以及不规律的
mealtimes could be harming your health.
就餐时间可能会损害您的健康。
We will also check out how medieval manuscripts are acting as biological time capsules.
我们还将了解中世纪手稿是如何充当生物时间胶囊的。
And finally, we will end on an incredibly inspiring story about a 22 -year -old fitness instructor who
最后，我们将以一个关于一位22岁健身教练的极其鼓舞人心的故事作为结束，她
is breaking down barriers and changing lives.
正在打破障碍并改变人们的生活。
All right, let's dive into our lead story.
好的，让我们深入探讨我们的头条新闻。
Scientists have announced some incredible findings from a Phase 2a clinical trial.
科学家们公布了一项 2a 期临床试验的一些不可思议的发现。
A drug candidate called RENTOSRTIB, which was originally discovered using artificial intelligence to
一种名为 RENTOSRTIB 的候选药物，最初是利用人工智能发现用来
treat a serious lung disease, has shown the ability to reverse key biological markers of aging.
治疗某种严重肺部疾病的，现已展示出逆转衰老关键生物标记的能力。
Wow, Zoe.
哇，佐伊。
A lung drug discovered by AI that can also slow down or reverse aging?
由 AI 发现的肺病药物还能延缓或逆转衰老？
That sounds almost too good to be true.
那听起来几乎好得令人难以置信。
How does a lung drug do that?
一款肺部药物是 怎么做到那一点的？
Well, RENTOSRTIB was designed to target idiopathic pulmonary fibrosis, which is a severe scarring of
嗯，RENTOSRTIB 旨在针对特发性肺纤维化，这是一种严重的
the lungs.
肺部疤痕化。
But because cellular scarring and aging share very similar biological pathways, the researchers
但是因为细胞疤痕化和衰老有着非常相似的生物通路，研究人员
decided to look closer.
决定进行更深入的观察。
They used what are called proteomega aging clocks to measure the biological age of the patient's proteins.
他们使用了所谓的蛋白质组学衰老时钟来测量患者蛋白质的生物学年龄。
They discovered that the drug actually reversed these aging markers.
他们发现这种药物实际上逆转了这些衰老标记。
I read about this study, and they used a specific word to describe this effect.
我读过关于这项研究的报道，他们用了一个具体的词来描述这种效果。
Gero -protective.
抗衰老保护的。
Zoe, can you explain what Gero -protective actually means for our English learners?
佐伊，你能解释一下 Gero-protective 对于我们的英语学习者来说究竟意味着什么吗？
Of course.
当然可以。
Let's break it down.
让我们来剖析一下。
Gero comes from the Greek word for old age, and protective means to defend or shield.
Gero 来自希腊语中的“老年”，而 protective 意思是防御或保护。
So a Gero -protective substance is something that actively shields your cells from the damage of
因此，抗衰老保护性物质是指能够主动保护细胞免受损伤的物质，这种损伤来自
aging, effectively slowing down or even reversing the biological aging process.
衰老，从而有效地减缓甚至逆转生物衰老过程。
Ah, Gero -protective.
啊，抗衰老保护。
That is a great word.
那真是个棒词。
So what is a good way to picture this in our minds?
那么在我们的脑海中构想这一点的最佳方式是什么呢？
Think of it like a software update for an old computer.
把它想象成一台旧电脑的软件更新。
Over time, the computer gets full of bugs, slows down, and the hardware gets worn out.
随着时间的推移，电脑变得满是漏洞、速度变慢，硬件也会磨损。
A Gero -protective drug acts like a highly advanced software update that clears out the digital
抗衰老药物就像是一个高度先进的软件更新，能够清理数字
trash, repairs the system errors, and makes the old hardware run like it is brand new again.
垃圾，修复系统错误，并让旧硬件再次如新般运行。
Gero -protective.
延缓衰老的。
That is a brilliant metaphor.
那真是一个精彩的比喻。
A software update for ourselves.
针对我们自己的软件更新。
It is amazing to think that AI is helping us find these solutions so much faster than traditional methods.
难以置信的是，人工智能正在帮助我们比传统方法更快地找到这些解决方案。
Gero -protective. Absolutely.
延缓衰老。确实如此。
It is a massive step forward for longevity science.
这是长寿科学迈出的巨大一步。
But speaking of keeping our bodies healthy, our next story is a crucial safety warning about a very
不过说到保持身体健康，我们的下一个故事是一个至关重要的安全警告，涉及一个非常
common kitchen ingredient, the sugar substitute called xylitol.
常见的 厨房原料，一种名为木糖醇的糖类替代品。
Gero - Wait, xylitol?
抗衰——等等，木糖醇？
I know that one.
我知道那个。
It's in almost every sugar -free chewing gum, toothpaste, and diet snack.
它几乎存在于每一种无糖口香糖、牙膏和减肥零食中。
What did the scientists find out about it?
科学家们对此有什么发现？
Gero -protective.
延缓衰老的。
A new study published in the European Heart Journal has linked high blood levels of xylitol to a
发表在《欧洲心脏杂志》上的一项新研究将血液中高浓度的木糖醇与
significantly increased risk of heart attacks and strokes.
显著增加的心脏病发作和中风风险联系起来。
The researchers found that xylitol can cause blood platelets to clot much more easily, which can
研究人员发现，木糖醇会使血液中的血小板更容易凝集，从而
block blood flow.
阻塞血流。
Gero -protective.
延缓衰老的。
Oh, that is scary.
哦，那太可怕了。
The news reports keep using the term cardiovascular risk.
新闻报道不断使用心血管风险这个词。
Can we pause to define cardiovascular?
我们能暂停一下来定义心血管这个词吗？
Gero -protective. Definitely.
延缓衰老。当然。
Cardiovascular is a combination of two parts.
心血管（Cardiovascular）是两部分的结合。
Cardio, which means relating to the heart, and vascular, which refers to the blood vessels, like
Cardio 意思是与心脏有关，而 vascular 指的是血管，比如
arteries and veins.
动脉和静脉。
So cardiovascular risk is the likelihood of developing diseases that affect your heart and blood
因此，心血管风险是指患上影响心脏和血液系统疾病的可能性
circulation system.
循环系统。
Cardio for heart, vascular for blood vessels.
Cardio 代表心脏，vascular 代表血管。
Got it.
明白了。
What is a good metaphor for this?
对此有什么好的比喻吗？
Imagine a building's heating system.
想象一下建筑物的供暖系统。
The heart is the central water pump, and the blood vessels are the copper pipes running through the walls.
心脏是中央水泵，而血管是贯穿墙壁的铜管。
Cardiovascular health is about keeping that main pump strong and ensuring the pipes stay clean and
心血管健康就是要保持主水泵强劲，并确保管道保持清洁和
free of blockages so the water can flow smoothly.
没有堵塞物，以便水能够顺畅流动。
And xylitol, unfortunately, makes the water in those pipes more likely to clump up and create clogs.
不幸的是，木糖醇会使这些管道中的水更容易凝集并造成堵塞。
That is a very serious warning for anyone who consumes a lot of diet products. Exactly.
对于任何大量食用减肥产品的人来说，这都是一个非常严重的警告。确实如此。
While more research is needed, experts suggest reading labels carefully and choosing natural
虽然还需要更多的研究，但专家建议仔细阅读标签并选择天然
sweeteners when possible.
尽可能选择天然甜味剂。
I will definitely be checking my chewing gum pack after we finish recording today.
今天录制结束后，我一定会检查我的口香糖包装。
Now, let's transition to our third story, which is also about what we consume, but more importantly,
现在，让我们过渡到我们的第三个故事，这同样与我们消耗的内容有关，但更重要的是，
when we consume it.
我们在什么时候食用它。
It is about a concept called eating jet lag.
这是关于一个被称为饮食时差的概念。
Yes, this is a fascinating study published in Nature.
是的，这是发表在《自然》杂志上一项令人着迷的研究。
Researchers found that having inconsistent mealtimes, especially eating breakfast at widely
研究人员发现，进食时间不规律，特别是在广泛
different times on weekdays versus weekends, is linked to a 29 % higher risk of mortality, especially
工作日与周末吃早餐的时间相差很大，会导致死亡率增加 29% 的风险，尤其是
for people over the age of 40.
对于 40 岁以上的人群而言。
A 29 % higher risk?
高出 29% 的风险？
That is a huge number.
那是一个巨大的数字。
Let me make sure I understand this.
让我确认一下我是否理解了这一点。
So if I eat breakfast at 7 in the morning on Monday, but then sleep in and eat breakfast at 11 on
所以如果我在周一早上 7 点吃早餐，但在周六睡觉睡到 11 点才吃
Saturday, my body experiences eating jet lag? Exactly.
周六，我的身体就会经历“进食时差”？一点也没错。
You're experiencing a mismatch between your social schedule and your body's internal biological
你正在经历社交日程与你体内生物不匹配的情况
clock, which is also called your circadian rhythm.
钟，这也被称为你的昼夜节律。
You see, our digestive organs, especially the liver, have their own daily schedule.
你看，我们的消化器官，特别是肝脏，都有它们自己的日常作息表。
When you eat at wildly different times, you throw those internal clocks completely out of sync.
当你吃饭的时间大相径庭时，就会让这些内部生物钟完全失去同步。
Ah, so it is like normal jet lag when you fly across the world.
啊，所以这就像飞半个地球时产生的普通时差一样。
But instead of confusing your eyes with light, you are confusing your stomach with food.
但你不是用光线混淆双眼，而是用食物混淆胃部。
Yes, that is the perfect way to describe it.
是的，这是最完美的描述方式。
Think of your digestive system as a highly organized factory.
把你的消化系统想象成一个高度井井有条的工厂。
The workers expect the raw materials to arrive at exactly 8 in the morning.
工人们期望原材料在早上 8 点整送达。
If you suddenly dump a massive shipment of materials on them at midnight or four hours late on the
如果你突然在午夜或者在周末推迟四个小时向他们倾倒大量货物
weekend, the factory descends into chaos.
周末，工厂就会陷入混乱。
The workers get stressed, mistakes are made, and eventually the machines break down.
工人感到压力山大，犯下错误，最终机器崩溃。
That is an amazing way to visualize it.
这是一个极其生动具象化的理解方式。
So consistency is key.
所以保持一致性是关键。
Even if we sleep in on Saturdays, we should try to keep our eating times relatively stable to keep
即使我们在周六睡懒觉，也应该尽量保持饮食时间相对稳定，以
our liver and heart happy. Precisely.
让我们的肝脏和心脏保持健康。完全正确。
Your body thrives on routine.
你的身体在规律作息中最能茁壮成长。
Now let's move from our internal clocks to the depths of history for our fourth story.
现在，让我们从体内生物钟转向历史深处，来看看我们的第四个故事。
Scientists have discovered that medieval manuscripts are actually biological time capsules.
科学家们发现，中世纪的手稿实际上是生物时间胶囊。
Medieval manuscripts?
中世纪的手稿？
You mean those beautiful old books written by hand hundreds of years ago?
你是说几百年前那些精美的手抄旧书？
How are they biological time capsules?
它们怎么会是生物时间胶囊呢？
Well, in the medieval period, books were not made of paper.
嗯，在中世纪时期，书本并不是用纸做的。
They were written on parchment, which is made from animal skins, usually sheep, goats, or cows.
它们是写在羊皮纸上的，羊皮纸由动物皮革制成，通常是绵羊、山羊或牛的皮。
Because of this, the pages contain preserved DNA of the animals.
因此，这些书页中包含着保存下来的动物 DNA。
Researchers recently analyzed these ancient pages and successfully recovered the genome of a deadly
研究人员最近分析了这些古老的书页，并成功复原了一种致命疾病的基因组
sheep pox virus from manuscripts dating back hundreds of years.
绵羊痘病毒，这些手稿可以追溯到数百年前。
That is incredible.
这太不可思议了。
So by analyzing the pages of ancient books, scientists can actually trace the evolutionary history
所以通过分析古书的书页，科学家实际上可以追溯演化历史
of diseases over thousands of years? Exactly.
数千年来疾病的发展？一点也没错。
It allows scientists to see how viruses mutated and spread throughout history.
它让科学家能够观察病毒在整个历史过程中是如何变异和传播的。
It's like finding a historical library of genetics hidden inside a library of literature.
这就像在文学图书馆里发现了一个隐藏的遗传学历史图书馆。
That is absolutely mind -blowing.
这简直太让人震撼了。
It shows how science can find answers in the most unexpected places.
这表明科学可以在最意想不到的地方找到答案。
Speaking of overcoming challenges and finding success in unexpected places, let's talk about our
说到克服挑战并在意想不到的地方取得成功，让我们聊聊我们的
final heartwarming story of the day.
今天的最后一个暖心故事。
This is a wonderful story about a 22 -year -old young man with Down syndrome who has officially become
这是一个美好的故事，讲述了一名患有唐氏综合征的 22 岁年轻人，他已正式成为
a certified fitness instructor.
一名获得认证的健身教练。
He is now leading classes of over 60 people at his local gym.
他现在在当地的健身房带领着 60 多人的课程。
Oh, I absolutely love this.
哦，我绝对喜欢这个故事。
Becoming a certified fitness instructor is not easy.
成为一名获得认证的健身教练并不容易。
There are intense physical and written tests.
这需要通过严格的体能和笔试。
To achieve that while living with Down syndrome is a massive accomplishment.
作为一名唐氏综合征患者能做到这一点，是一项巨大的成就。
It truly is.
这确实是。
He worked incredibly hard, studied for months, and proved that physical and cognitive differences do
他极其努力地工作和学习了几个月，证明了身体和认知上的差异确实
not have to limit your dreams.
不必限制你的梦想。
His classes are now packed with people who find his energy and dedication deeply motivating.
他的课堂现在挤满了人，他们觉得他的活力和奉献极具激励性。
That is so beautiful.
那真是太美好了。
It is the ultimate proof that with the right support, determination, and hard work, we can shatter
这是最终的证明：有了适当的支持、决心和努力，我们就能够粉碎
any ceiling.
任何天花板。
What an incredibly positive note to start our day.
以如此难以置信积极的基调开启我们的一天。
It really is.
确实是的。
And that brings us to the end of our news stories for today.
这也让我们结束了今天的新闻故事。
But don't go away just yet, listeners.
但是先不要走开，听众朋友们。
It is time to test what we have learned today with our quick knowledge quiz. Yes.
是时候用我们的快速知识测验来检验我们今天学到的内容了。是的。
Let's do a quick question based on our vocabulary and stories today.
让我们根据今天的词汇和故事做一道快速问答。
All right.
好的。
Here's the question.
这是问题。
What is the meaning of the medical term cardiovascular, and what was the simple metaphor we used to
医学术语心血管的含义是什么，我们用来
explain it?
解释它的简单比喻又是什么？
I will give our listeners a few seconds to think about it. Ready?
我会给听众几秒钟的时间思考一下。准备好了吗？
The term cardiovascular relates to the heart and blood vessels.
心血管一词与心脏和血管有关。
The metaphor we used was a building's central heating system, where the heart is the water pump and
我们使用的比喻是建筑物的中央供暖系统，其中心脏是水泵，
the blood vessels are the plumbing pipes.
而血管则是管道水管。
Spot on, Zoe.
完全正确，佐伊。
And now we have an open, thought -provoking question for our community.
现在我们为我们的社区准备了一个开放且引人深思的问题。
How do you feel about the concept of eating jet lag?
你对饮食时差这个概念有什么看法？
Do you keep a strict eating schedule every day, or do you love sleeping in and having a late
你每天都保持严格的饮食作息，还是喜欢睡懒觉、吃个晚一点的
breakfast on weekends?
在周末吃早餐？
How do you think this affects your energy levels?
你认为这会如何影响你的精力水平？
That is a great question.
那真是个棒极了的问题。
Listeners, please write down your answers in the comments section below, or take a look at what
听众朋友们，请在下方评论区写下您的答案，或者看看
other listeners from around the world are saying.
来自世界各地的其他听众在说什么。
It is a fantastic way to practice your English writing and connect with our global community. Absolutely.
这是练习英语写作并与我们全球社区建立联系的绝佳方式。确实如此。
And remember, if you want to review the vocabulary, read the sentences, or study the grammar, the
请记住，如果您想复习词汇、阅读句子或学习语法，
full English transcript of today's episode is published on our official WeChat public account, TalkCast.
今天节目的英文完整逐字稿已发布在我们的官方微信公众号 TalkCast 上。
Please check it out.
请查看一下。
Thank you all so much for your warm feedback, comments, and incredible support.
非常感谢大家温暖的反馈、评论和难以置信的支持。
Don't forget to subscribe to TalkCast and share this episode with your friends who are also learning English.
别忘了订阅 TalkCast，并将本集分享给您同样在学习英语的朋友们。
Have a wonderful, healthy, and highly productive day ahead, everyone.
祝大家接下来度过精彩、健康且非常富有成效的一天。
See you tomorrow.
明天见。
Goodbye, everyone.
再见，大家。
Keep learning and stay curious.
保持学习，保持好奇。
